ZHX3

Across TCGA patient cohorts, ZHX3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,016 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZHX3-associated proteins across cancer lineages are ISG20, PLCG1, and APBB2. Each is linked with ZHX3 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZHX3-to-partner and partner-to-ZHX3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZHX3 versus ISG20 in BRCA, with a Pearson correlation of -0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZHX3→partner) and Y-score (partner→ZHX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ISG20 →	-0.761	-0.527	<.001	<.001	3	6
COAD	PLCG1 →	+0.299	+0.793	<.001	<.001	3	6
BRCA	APBB2 →	+0.391	+0.447	<.001	<.001	3	5
GBM	ZHX3_S680 →	+0.609	+0.803	<.001	<.001	3	5
OV	VCL_Y822 →	+1.423	+1.279	<.001	.001	3	5
BRCA	ACSS2 →	+0.382	+0.419	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,016 associations by consensus.

ZHX3 vs ISG20 — BRCA

Explore this scatter interactively →