ZHX3

Across TCGA cell cohorts, ZHX3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,589 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ZHX3-associated GO terms across cancer lineages are Response to oscillatory fluid shear stress, Cellular response to oscillatory fluid shear stress, and Vascular endothelial cell response to oscillatory fluid shear stress. Each is linked with ZHX3 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZHX3-to-partner and partner-to-ZHX3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to oscillatory fluid shear stress grouped by ZHX3-low versus ZHX3-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZHX3→partner) and Y-score (partner→ZHX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Response to oscillatory fluid shear stress →	+0.186	+1.021	.003	<.001	3	14
KIDNEY	Cellular response to oscillatory fluid shear stress →	+0.186	+1.021	.003	<.001	3	14
KIDNEY	Vascular endothelial cell response to oscillatory fluid shear stress →	+0.186	+1.021	.003	<.001	3	14
URINARY_TRACT	Protein depolymerization →	+0.141	+1.194	.001	.002	3	14
BONE	Positive regulation of cell-substrate junction organization →	+0.142	+1.097	<.001	<.001	3	14
BONE	Negative regulation of Rho protein signal transduction →	+0.237	+1.483	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,589 associations by consensus.

Response to oscillatory fluid shear stress by ZHX3 expression — KIDNEY

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