ZHX2

Across TCGA cell cohorts, ZHX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,553 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZHX2-associated GO terms across cancer lineages are Glutamatergic neuron differentiation, Lymphocyte costimulation, and Establishment of endothelial intestinal barrier. Each is linked with ZHX2 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZHX2-to-partner and partner-to-ZHX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glutamatergic neuron differentiation grouped by ZHX2-low versus ZHX2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZHX2→partner) and Y-score (partner→ZHX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Glutamatergic neuron differentiation →	+1.759	+2.782	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Lymphocyte costimulation →	+0.161	+1.107	.002	.005	2	11
OVARY	Establishment of endothelial intestinal barrier →	+0.172	+1.704	<.001	.003	3	10
SKIN	Protein transport into membrane raft →	+0.609	+1.085	.002	.002	3	9
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.114	+1.932	<.001	<.001	3	9
SOFT_TISSUE	Apoptotic signaling pathway →	+0.050	+1.488	.003	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,553 associations by consensus.

Glutamatergic neuron differentiation by ZHX2 expression — BLOOD_Lymphoma

Explore this box plot interactively →