ZGRF1

Across TCGA cell cohorts, ZGRF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,658 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZGRF1-associated GO terms across cancer lineages are Regulation of centrosome duplication, Regulation of metaphase/anaphase transition of cell cycle, and Regulation of mitotic metaphase/anaphase transition. Each is linked with ZGRF1 in more than 19 cancer types. Because this analysis shows association rather than direction, both ZGRF1-to-partner and partner-to-ZGRF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of centrosome duplication grouped by ZGRF1-low versus ZGRF1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZGRF1→partner) and Y-score (partner→ZGRF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of centrosome duplication →	+0.124	+1.481	<.001	<.001	3	20
OESOPHAGUS	Regulation of metaphase/anaphase transition of cell cycle →	+0.175	+1.170	<.001	<.001	3	20
OESOPHAGUS	Regulation of mitotic metaphase/anaphase transition →	+0.147	+0.841	<.001	.003	3	20
BONE	Regulation of chromosome organization →	+0.092	+1.090	.003	<.001	3	20
OESOPHAGUS	Regulation of sister chromatid segregation →	+0.133	+0.895	<.001	.001	3	20
OESOPHAGUS	Spindle assembly →	+0.128	+1.078	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,658 associations by consensus.

Regulation of centrosome duplication by ZGRF1 expression — BONE

Explore this box plot interactively →