ZGPAT

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZGPAT mutation is significantly associated with the RNA expression of many other genes, with 943 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZGPAT-associated genes across cancer lineages are RSL24D1P4, RNY4P23, and RN7SL442P. Each is linked with ZGPAT in more than 2 cancer types. Because this analysis shows association rather than direction, both ZGPAT-to-partner and partner-to-ZGPAT results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZGPAT→partner) and Y-score (partner→ZGPAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIRPRSL24D1P4 →+0.161+6.355<.001<.00133
LUADRNY4P23 →+0.585+4.105<.001.00133
UCECRN7SL442P →+0.434+2.393<.001<.00133
COADMTCYBP45 →+0.173+5.149<.001.00133
BRCAZACNP1 →+0.048+5.064<.001.00432
CESCYAP1P2 →+0.097+5.418<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 943 associations by consensus.

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