Across TCGA patient cohorts, ZGPAT mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZGPAT-associated genes across cancer lineages are Rb_pS807_S811, PCNA, and S6_pS240_S244. Each is linked with ZGPAT in more than 3 cancer types. Because this analysis shows association rather than direction, both ZGPAT-to-partner and partner-to-ZGPAT results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZGPAT→partner) and Y-score (partner→ZGPAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Rb_pS807_S811 →	+0.661	+2.815	.022	.036	3	3
UCEC	PCNA →	+0.251	+3.459	.020	.005	3	3
UCEC	S6_pS240_S244 →	+0.651	+3.013	.001	.018	3	2
COAD	ASNS →	+0.834	+2.815	<.001	.036	3	2
UCEC	Cyclin-B1 →	+0.821	+3.459	.003	.005	1	4
UCEC	c-Kit →	-0.250	-2.321	.033	.035	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Exploration

ZGPAT survival (RNA) · tumor vs normal (RNA) · all ZGPAT data types