Across TCGA patient cohorts, ZGLP1 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZGLP1-associated genes across cancer lineages are MPP, cDC, and Th2 cells. Each is linked with ZGLP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZGLP1-to-partner and partner-to-ZGLP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZGLP1→partner) and Y-score (partner→ZGLP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MPP →	+0.027	+3.510	.007	.017	3	1
UCEC	cDC →	+0.140	+2.818	<.001	.035	3	1
UCEC	Th2 cells →	+0.250	+2.177	.005	.035	3	1
UCEC	Endothelial cells →	-0.041	-2.279	.030	.036	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

ZGLP1 survival (RNA) · tumor vs normal (RNA) · all ZGLP1 data types