Across TCGA cell cohorts, ZGLP1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZGLP1-associated genes across cancer lineages are OR6Q1, TACR3, and OC90. Each is linked with ZGLP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZGLP1-to-partner and partner-to-ZGLP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZGLP1→partner) and Y-score (partner→ZGLP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR6Q1 →	+0.030	+6.022	<.001	.001	3	1
BLOOD_Leukemia	TACR3 →	+0.038	+5.060	<.001	.001	3	1
BLOOD_Leukemia	OC90 →	+0.012	+5.786	<.001	<.001	3	1
BLOOD_Leukemia	OR1D4 →	+0.046	+4.539	<.001	.007	3	1
BLOOD_Leukemia	DIRAS2 →	+0.152	+4.087	<.001	.009	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

ZGLP1 survival (RNA) · tumor vs normal (RNA) · all ZGLP1 data types