ZG16B

Across TCGA pan-cancer cohorts, ZG16B mass-spec protein differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of ZG16B’s most consistent transcriptional readouts.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where ZG16B mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types ZG16B is over-expressed in tumor, although a few such as HNSC show the opposite, repressed pattern.

PDAC and HNSC are the cancer types where ZG16B tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZG16B mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
PDAC	Female	All	+2.250	<.001	8	view →
HNSC	Male	II,III,IV	−1.650	<.001	8	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

ZG16B–PDAC

Open the PDAC breakdown →