ZG16B

Across TCGA patient cohorts, ZG16B mutation is significantly associated with the RNA expression of many other genes, with 1,289 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible ZG16B-associated genes across cancer lineages are MIR4294, RBM22P6, and CACTIN. Each is linked with ZG16B in more than 1 cancer types. Because this analysis shows association rather than direction, both ZG16B-to-partner and partner-to-ZG16B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4294 grouped by ZG16B-low versus ZG16B-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZG16B→partner) and Y-score (partner→ZG16B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIR4294 →	+0.492	+3.024	<.001	.009	3	2
SKCM	RBM22P6 →	+0.020	+3.135	<.001	.001	3	2
UCEC	CACTIN →	+0.548	+3.202	<.001	.009	3	2
SKCM	ELL →	+0.359	+2.757	.005	.003	3	2
SKCM	LRRC42 →	+0.609	+3.510	.001	.002	3	2
SKCM	ST3GAL3 →	+0.433	+2.757	.007	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,289 associations by consensus.

MIR4294 by ZG16B expression — LUAD

Explore this box plot interactively →