ZG16B

Across TCGA patient cohorts, ZG16B mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZG16B-associated genes across cancer lineages are B-cells, MPP, and NKT. Each is linked with ZG16B in more than 1 cancer types. Because this analysis shows association rather than direction, both ZG16B-to-partner and partner-to-ZG16B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B-cells grouped by ZG16B-low versus ZG16B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZG16B→partner) and Y-score (partner→ZG16B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	B-cells →	+0.031	+1.836	.026	.033	3	2
SKCM	MPP →	+0.012	+2.756	.038	<.001	3	1
SKCM	NKT →	-0.118	-2.302	.025	.034	3	1
UCEC	Epithelial cells →	-0.151	-3.161	<.001	.019	2	1
UCEC	CLP →	-0.072	-3.279	.027	.011	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

B-cells by ZG16B expression — UCEC

Explore this box plot interactively →