ZG16B

Across TCGA cell cohorts, ZG16B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,421 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ZG16B-associated GO terms across cancer lineages are Regulation of tolerance induction dependent upon immune response, T cell mediated immunity, and Negative regulation of protein polymerization. Each is linked with ZG16B in more than 10 cancer types. Because this analysis shows association rather than direction, both ZG16B-to-partner and partner-to-ZG16B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of tolerance induction dependent upon immune response grouped by ZG16B-low versus ZG16B-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZG16B→partner) and Y-score (partner→ZG16B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of tolerance induction dependent upon immune response →	+0.877	+2.460	.005	<.001	2	11
URINARY_TRACT	T cell mediated immunity →	+0.194	+2.732	<.001	<.001	3	8
URINARY_TRACT	Negative regulation of protein polymerization →	+0.171	+2.886	<.001	<.001	3	8
URINARY_TRACT	Nail development →	+0.391	+2.861	.003	<.001	3	8
PANCREAS	Skin morphogenesis →	+0.198	+2.730	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Positive regulation of lipid metabolic process →	+0.075	+2.309	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,421 associations by consensus.

Regulation of tolerance induction dependent upon immune response by ZG16B expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →