ZFYVE9

Across TCGA cell cohorts, ZFYVE9 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,912 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZFYVE9-associated GO terms across cancer lineages are Host-mediated perturbation of viral process, Heterochromatin organization, and Regulation of smoothened signaling pathway. Each is linked with ZFYVE9 in more than 11 cancer types. Because this analysis shows association rather than direction, both ZFYVE9-to-partner and partner-to-ZFYVE9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Host-mediated perturbation of viral process grouped by ZFYVE9-low versus ZFYVE9-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFYVE9→partner) and Y-score (partner→ZFYVE9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Host-mediated perturbation of viral process →	+0.091	+1.129	<.001	<.001	3	12
STOMACH	Heterochromatin organization →	+0.088	+0.957	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Regulation of smoothened signaling pathway →	+0.069	+0.845	.001	.003	3	12
STOMACH	Pre-miRNA processing →	+0.175	+1.475	<.001	<.001	3	11
STOMACH	Heterochromatin formation →	+0.091	+0.989	<.001	<.001	3	11
BLOOD_Myeloma	Autophagosome assembly →	+0.082	+1.011	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,912 associations by consensus.

Host-mediated perturbation of viral process by ZFYVE9 expression — STOMACH

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