ZFYVE26

Across TCGA patient cohorts, ZFYVE26 mutation is significantly associated with the RNA expression of many other genes, with 4,148 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFYVE26-associated genes across cancer lineages are FGD5, PKN3, and PLB1. Each is linked with ZFYVE26 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZFYVE26-to-partner and partner-to-ZFYVE26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FGD5 grouped by ZFYVE26-low versus ZFYVE26-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFYVE26→partner) and Y-score (partner→ZFYVE26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FGD5 →	-0.385	-1.234	.004	.001	3	4
SKCM	PKN3 →	+0.492	+2.179	.003	.001	3	4
LUAD	PLB1 →	-0.445	-3.040	.002	<.001	3	4
UCEC	CCDC89 →	-0.583	-1.618	<.001	<.001	3	4
UCEC	EMID1 →	-0.803	-1.989	<.001	<.001	3	4
UCEC	TAFA5 →	-0.592	-1.104	.004	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,148 associations by consensus.

FGD5 by ZFYVE26 expression — UCEC

Explore this box plot interactively →