ZFYVE26

Across TCGA cell cohorts, ZFYVE26 mutation is significantly associated with the RNA expression of many other genes, with 238 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZFYVE26-associated genes across cancer lineages are CLLU1-AS1, HAS2, and SERPINA7. Each is linked with ZFYVE26 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFYVE26-to-partner and partner-to-ZFYVE26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLLU1-AS1 grouped by ZFYVE26-low versus ZFYVE26-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFYVE26→partner) and Y-score (partner→ZFYVE26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	CLLU1-AS1 →	+0.059	+3.392	<.001	.007	3	2
LUNG_SCLC	HAS2 →	+0.436	+2.724	<.001	.005	3	2
LUNG_NSCLC_LUAD	SERPINA7 →	+0.005	+3.228	<.001	.003	3	2
LUNG_NSCLC_LUAD	TEX49 →	+0.078	+3.281	<.001	<.001	3	2
LARGE_INTESTINE	CDK2AP1 →	+0.584	+2.158	.003	.004	3	2
LARGE_INTESTINE	LAX1 →	+0.071	+2.244	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 238 associations by consensus.

CLLU1-AS1 by ZFYVE26 expression — OESOPHAGUS

Explore this box plot interactively →