ZFYVE21

Across TCGA patient cohorts, ZFYVE21 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,066 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ZFYVE21-associated proteins across cancer lineages are CDC42BPB, PPP1R13B, and BAG5. Each is linked with ZFYVE21 in more than 8 cancer types. Because this analysis shows association rather than direction, both ZFYVE21-to-partner and partner-to-ZFYVE21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZFYVE21 versus CDC42BPB in BRCA, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFYVE21→partner) and Y-score (partner→ZFYVE21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CDC42BPB →	+0.286	+0.377	<.001	<.001	3	9
CCRCC	PPP1R13B →	+0.365	+0.539	<.001	<.001	3	7
OV	BAG5 →	+0.349	+0.435	<.001	.007	2	8
OV	AKT1 →	+0.353	+0.500	.004	<.001	3	7
HNSC	SETD3 →	+0.269	+0.627	<.001	<.001	3	6
LSCC	MTA1 →	+0.360	+0.536	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,066 associations by consensus.

ZFYVE21 vs CDC42BPB — BRCA

Explore this scatter interactively →