ZFYVE21

Across TCGA patient cohorts, ZFYVE21 protein abundance is significantly associated with the RNA expression of many other genes, with 12,201 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZFYVE21-associated genes across cancer lineages are GSTM5, CALM1, and RAD51AP1. Each is linked with ZFYVE21 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZFYVE21-to-partner and partner-to-ZFYVE21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZFYVE21 versus GSTM5 in UCEC, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFYVE21→partner) and Y-score (partner→ZFYVE21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GSTM5 →	+0.880	+0.429	<.001	<.001	3	6
GBM	CALM1 →	+0.577	+0.363	<.001	<.001	3	6
LUAD	RAD51AP1 →	-1.163	-0.331	<.001	<.001	3	6
BRCA	PTPN21 →	+0.788	+0.250	<.001	<.001	3	6
CCRCC	LHFPL6 →	+0.972	+0.271	.001	.003	3	6
UCEC	PGM5 →	+1.167	+0.354	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,201 associations by consensus.

ZFYVE21 vs GSTM5 — UCEC

Explore this scatter interactively →