ZFYVE21

Across TCGA cell cohorts, ZFYVE21 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,092 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ZFYVE21-associated GO terms across cancer lineages are Schwann cell differentiation, Schwann cell development, and ERBB3 signaling pathway. Each is linked with ZFYVE21 in more than 12 cancer types. Because this analysis shows association rather than direction, both ZFYVE21-to-partner and partner-to-ZFYVE21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Schwann cell differentiation grouped by ZFYVE21-low versus ZFYVE21-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFYVE21→partner) and Y-score (partner→ZFYVE21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Schwann cell differentiation →	+0.155	+1.053	<.001	<.001	3	13
URINARY_TRACT	Schwann cell development →	+0.138	+0.873	<.001	.001	3	12
LARGE_INTESTINE	ERBB3 signaling pathway →	+0.171	+0.557	<.001	.003	3	10
LARGE_INTESTINE	ERBB2-ERBB3 signaling pathway →	+0.171	+0.557	<.001	.003	3	10
BLOOD_Lymphoma	Glycerolipid biosynthetic process →	+0.035	+0.872	<.001	<.001	3	10
OESOPHAGUS	Viral gene expression →	+0.077	+0.865	.008	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,092 associations by consensus.

Schwann cell differentiation by ZFYVE21 expression — URINARY_TRACT

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