ZFYVE19

Across TCGA patient cohorts, ZFYVE19 mutation is significantly associated with the RNA expression of many other genes, with 522 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFYVE19-associated genes across cancer lineages are GNG5P5, AMY2A, and RNA5SP354. Each is linked with ZFYVE19 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFYVE19-to-partner and partner-to-ZFYVE19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GNG5P5 grouped by ZFYVE19-low versus ZFYVE19-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFYVE19→partner) and Y-score (partner→ZFYVE19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	GNG5P5 →	+0.084	+4.296	<.001	.006	3	2
BLCA	AMY2A →	+0.143	+3.039	.001	.008	3	2
SKCM	RNA5SP354 →	+0.355	+3.562	<.001	.001	3	2
SKCM	SNRPCP9 →	+0.217	+2.769	.001	.008	3	2
UCEC	RANP2 →	+0.239	+2.371	<.001	.003	3	2
COAD	RPL23AP69 →	+0.216	+3.738	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 522 associations by consensus.

GNG5P5 by ZFYVE19 expression — BLCA

Explore this box plot interactively →