ZFYVE19

Across TCGA patient cohorts, ZFYVE19 mutation is significantly associated with the immune_cell of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFYVE19-associated genes across cancer lineages are Monocytes, Neutrophils, and NKT. Each is linked with ZFYVE19 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFYVE19-to-partner and partner-to-ZFYVE19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monocytes grouped by ZFYVE19-low versus ZFYVE19-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFYVE19→partner) and Y-score (partner→ZFYVE19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Monocytes →	+0.013	+5.225	<.001	.001	3	1
SKCM	Neutrophils →	+0.016	+2.352	.010	.024	3	1
SKCM	NKT →	+0.237	+2.826	<.001	.035	3	1
UCEC	CD8+ naive T-cells →	+0.045	+3.202	<.001	.009	3	1
UCEC	Class-switched memory B-cells →	-0.057	-3.044	.040	.014	3	1
UCEC	lymphatic Endothelial cells →	-0.024	-3.138	.038	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Monocytes by ZFYVE19 expression — SKCM

Explore this box plot interactively →