ZFYVE19

Across TCGA cell cohorts, ZFYVE19 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,914 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ZFYVE19-associated GO terms across cancer lineages are Mitotic cytokinesis checkpoint signaling, Xenophagy, and Midbody abscission. Each is linked with ZFYVE19 in more than 14 cancer types. Because this analysis shows association rather than direction, both ZFYVE19-to-partner and partner-to-ZFYVE19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic cytokinesis checkpoint signaling grouped by ZFYVE19-low versus ZFYVE19-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFYVE19→partner) and Y-score (partner→ZFYVE19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Mitotic cytokinesis checkpoint signaling →	+0.210	+1.049	<.001	<.001	3	15
LUNG_SCLC	Xenophagy →	+0.209	+0.512	.001	<.001	3	12
OESOPHAGUS	Midbody abscission →	+0.114	+0.911	<.001	<.001	3	10
OVARY	Regulation of translation at postsynapse, modulating synaptic transmission →	+0.092	+0.883	.005	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.085	-0.650	.006	.003	3	10
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.105	-0.587	<.001	.008	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,914 associations by consensus.

Mitotic cytokinesis checkpoint signaling by ZFYVE19 expression — URINARY_TRACT

Explore this box plot interactively →