ZFYVE19

Across TCGA cell cohorts, ZFYVE19 mutation is significantly associated with the RNA expression of many other genes, with 56 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible ZFYVE19-associated genes across cancer lineages are OR56A1, CST5, and MROH2B. Each is linked with ZFYVE19 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFYVE19-to-partner and partner-to-ZFYVE19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR56A1 grouped by ZFYVE19-low versus ZFYVE19-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFYVE19→partner) and Y-score (partner→ZFYVE19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	OR56A1 →	+0.059	+4.736	<.001	.009	3	2
BLOOD_Lymphoma	CST5 →	+0.532	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	MROH2B →	+0.116	+5.643	<.001	.002	3	1
LARGE_INTESTINE	OR10W1 →	+0.022	+4.977	<.001	.007	3	1
UPPER_AERODIGESTIVE_TRACT	AGXT2 →	+0.026	+4.736	<.001	.009	3	1
UPPER_AERODIGESTIVE_TRACT	PRAMEF2 →	+0.182	+4.736	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 56 associations by consensus.

OR56A1 by ZFYVE19 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →