ZFYVE16

Across TCGA patient cohorts, ZFYVE16 protein abundance is significantly associated with the RNA expression of many other genes, with 15,409 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZFYVE16-associated genes across cancer lineages are VSIG4, TGFBR2, and TLR8. Each is linked with ZFYVE16 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZFYVE16-to-partner and partner-to-ZFYVE16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZFYVE16 versus VSIG4 in GBM, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFYVE16→partner) and Y-score (partner→ZFYVE16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	VSIG4 →	+1.474	+0.256	<.001	<.001	3	6
GBM	TGFBR2 →	+0.900	+0.257	<.001	<.001	3	6
GBM	TLR8 →	+1.286	+0.221	<.001	<.001	3	5
LSCC	ATP8B4 →	+0.893	+0.305	<.001	<.001	3	5
LSCC	ABI3 →	+0.979	+0.207	<.001	<.001	3	5
GBM	MS4A6A →	+1.281	+0.205	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,409 associations by consensus.

ZFYVE16 vs VSIG4 — GBM

Explore this scatter interactively →