ZFYVE16

Across TCGA patient cohorts, ZFYVE16 mutation is significantly associated with the RNA expression of many other genes, with 4,675 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFYVE16-associated genes across cancer lineages are ZNF736P7Y, NF1P10, and ING2. Each is linked with ZFYVE16 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZFYVE16-to-partner and partner-to-ZFYVE16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF736P7Y grouped by ZFYVE16-low versus ZFYVE16-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFYVE16→partner) and Y-score (partner→ZFYVE16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	ZNF736P7Y →	+0.066	+3.621	<.001	.006	3	3
CESC	NF1P10 →	+0.362	+5.569	<.001	.002	3	3
UCEC	ING2 →	+0.472	+2.078	<.001	<.001	3	3
UCEC	GEMIN2 →	+0.443	+1.558	<.001	<.001	3	3
UCEC	TNFRSF10B →	+0.377	+1.502	.003	.006	3	3
BLCA	MIR196A1 →	+1.374	+3.648	.004	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,675 associations by consensus.

ZNF736P7Y by ZFYVE16 expression — STAD

Explore this box plot interactively →