ZFYVE16

Across TCGA cell cohorts, ZFYVE16 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,905 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZFYVE16-associated GO terms across cancer lineages are Positive regulation of maintenance of sister chromatid cohesion, Positive regulation of maintenance of mitotic sister chromatid cohesion, and Establishment of protein localization to organelle. Each is linked with ZFYVE16 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZFYVE16-to-partner and partner-to-ZFYVE16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of maintenance of sister chromatid cohesion grouped by ZFYVE16-low versus ZFYVE16-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFYVE16→partner) and Y-score (partner→ZFYVE16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of maintenance of sister chromatid cohesion →	+0.154	+0.726	<.001	.001	3	16
SOFT_TISSUE	Positive regulation of maintenance of mitotic sister chromatid cohesion →	+0.154	+0.726	<.001	.001	3	16
OVARY	Establishment of protein localization to organelle →	+0.048	+0.900	<.001	<.001	3	15
BLOOD_Myeloma	Positive regulation of organelle assembly →	+0.087	+0.994	<.001	<.001	3	15
OESOPHAGUS	Protein targeting to vacuole →	+0.104	+1.202	.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.058	+1.014	.005	<.001	2	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,905 associations by consensus.

Positive regulation of maintenance of sister chromatid cohesion by ZFYVE16 expression — SOFT_TISSUE

Explore this box plot interactively →