ZFYVE16

Across TCGA cell cohorts, ZFYVE16 mutation is significantly associated with the RNA expression of many other genes, with 332 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZFYVE16-associated genes across cancer lineages are KIF27, FCAMR, and DTHD1. Each is linked with ZFYVE16 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFYVE16-to-partner and partner-to-ZFYVE16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KIF27 grouped by ZFYVE16-low versus ZFYVE16-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFYVE16→partner) and Y-score (partner→ZFYVE16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KIF27 →	+0.583	+3.064	.002	.009	3	2
SKIN	FCAMR →	+0.060	+2.876	<.001	.009	3	2
BREAST	DTHD1 →	+0.036	+4.421	<.001	.004	3	1
LARGE_INTESTINE	PLA2G3 →	+1.118	+2.125	<.001	.008	3	1
LARGE_INTESTINE	DEPDC5 →	+0.508	+3.459	.005	.001	3	1
LARGE_INTESTINE	IFT27 →	+0.793	+3.234	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 332 associations by consensus.

KIF27 by ZFYVE16 expression — LARGE_INTESTINE

Explore this box plot interactively →