Across TCGA patient cohorts, ZFY RNA expression is significantly associated with the go_rna of many other GO terms, with 6,497 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible ZFY-associated GO terms across cancer lineages are Sequestering of actin monomers, lncRNA-mediated post-transcriptional gene silencing, and Regulation of miRNA catabolic process. Each is linked with ZFY in more than 19 cancer types. Because this analysis shows association rather than direction, both ZFY-to-partner and partner-to-ZFY results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFY→partner) and Y-score (partner→ZFY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Sequestering of actin monomers →	-0.091	-1.995	<.001	<.001	3	20
GBM	lncRNA-mediated post-transcriptional gene silencing →	+0.076	+1.451	<.001	<.001	3	13
GBM	Regulation of miRNA catabolic process →	+0.054	+1.294	<.001	<.001	3	12
TGCT	Sex-chromosome dosage compensation →	+0.042	+0.928	.001	<.001	3	11
TGCT	Protein localization to endosome →	+0.047	+0.605	<.001	<.001	3	10
TGCT	Nuclear-transcribed mRNA catabolic process, deadenylation-independent decay →	+0.091	+0.980	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,497 associations by consensus.

Exploration

ZFY survival (RNA) · tumor vs normal (RNA) · all ZFY data types