ZFR2

Across TCGA patient cohorts, ZFR2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,258 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZFR2-associated genes across cancer lineages are GZMB, CR2, and IFIT3. Each is linked with ZFR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFR2-to-partner and partner-to-ZFR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZFR2 versus GZMB in GBM, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFR2→partner) and Y-score (partner→ZFR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GZMB →	+0.900	+1.556	.001	.003	3	1
GBM	CR2 →	+0.122	+1.184	.001	.007	3	1
GBM	IFIT3 →	+1.330	+1.196	.009	.004	3	1
GBM	NPHS1 →	+0.116	+1.158	.006	.006	3	1
GBM	UVSSA →	+0.546	+1.198	<.001	.004	3	1
GBM	FSTL5 →	+1.684	+1.932	.008	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,258 associations by consensus.

ZFR2 vs GZMB — GBM

Explore this scatter interactively →