ZFR2

Across TCGA patient cohorts, ZFR2 mutation is significantly associated with the RNA expression of many other genes, with 1,262 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFR2-associated genes across cancer lineages are RNU7-136P, SLC25A51P3, and OR4G2P. Each is linked with ZFR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZFR2-to-partner and partner-to-ZFR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-136P grouped by ZFR2-low versus ZFR2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFR2→partner) and Y-score (partner→ZFR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU7-136P →	+0.503	+4.554	<.001	.009	3	3
LIHC	SLC25A51P3 →	+0.062	+5.355	<.001	.005	3	2
SKCM	OR4G2P →	+0.014	+3.993	<.001	.008	3	2
SKCM	AMY1C →	+0.200	+4.485	<.001	.004	3	2
SKCM	RNU6-302P →	+0.233	+2.668	.002	.009	3	2
SKCM	TCP11X2 →	+0.005	+4.485	.009	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,262 associations by consensus.

RNU7-136P by ZFR2 expression — LUAD

Explore this box plot interactively →