ZFR2

Across TCGA cell cohorts, ZFR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,934 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ZFR2-associated GO terms across cancer lineages are Negative regulation of RNA splicing, Positive regulation of adiponectin secretion, and Lipoprotein transport. Each is linked with ZFR2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZFR2-to-partner and partner-to-ZFR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of RNA splicing grouped by ZFR2-low versus ZFR2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFR2→partner) and Y-score (partner→ZFR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Negative regulation of RNA splicing →	+0.047	+1.426	.009	.002	3	5
OVARY	Positive regulation of adiponectin secretion →	-0.951	-1.018	.001	.008	3	5
OVARY	Lipoprotein transport →	+0.110	+1.078	.002	.002	3	5
SOFT_TISSUE	Regulation of calcium ion transport into cytosol →	-0.244	-0.808	<.001	.002	3	4
BONE	Neural tube formation →	+0.105	+1.880	<.001	.001	3	4
BONE	Regulation of monocyte aggregation →	-1.335	-1.447	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,934 associations by consensus.

Negative regulation of RNA splicing by ZFR2 expression — LUNG_SCLC

Explore this box plot interactively →