ZFR2

Across TCGA cell cohorts, ZFR2 mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZFR2-associated genes across cancer lineages are OR10A5, ADAM7, and IFNA14. Each is linked with ZFR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFR2-to-partner and partner-to-ZFR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10A5 grouped by ZFR2-low versus ZFR2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFR2→partner) and Y-score (partner→ZFR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR10A5 →	+0.025	+3.930	<.001	.003	3	2
LARGE_INTESTINE	ADAM7 →	+0.004	+3.345	<.001	.007	3	2
SOFT_TISSUE	IFNA14 →	+0.024	+4.369	<.001	.008	3	1
BONE	DYTN →	+0.340	+5.169	<.001	.004	3	1
BONE	OR4A47 →	+0.006	+5.169	<.001	.004	3	1
LUNG_NSCLC_LUSC	LY6G6F →	+0.036	+4.643	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

OR10A5 by ZFR2 expression — SKIN

Explore this box plot interactively →