ZFR

Across TCGA cell cohorts, ZFR RNA expression is significantly associated with the go_rna of many other GO terms, with 3,521 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZFR-associated GO terms across cancer lineages are Protein localization to nuclear inner membrane, Establishment of mitotic sister chromatid cohesion, and Centrosome cycle. Each is linked with ZFR in more than 17 cancer types. Because this analysis shows association rather than direction, both ZFR-to-partner and partner-to-ZFR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to nuclear inner membrane grouped by ZFR-low versus ZFR-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFR→partner) and Y-score (partner→ZFR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Protein localization to nuclear inner membrane →	+0.180	+0.555	<.001	.002	3	18
UPPER_AERODIGESTIVE_TRACT	Establishment of mitotic sister chromatid cohesion →	+0.110	+0.689	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Centrosome cycle →	+0.081	+0.875	<.001	.001	3	16
UPPER_AERODIGESTIVE_TRACT	Nucleic acid transport →	+0.116	+1.181	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	RNA transport →	+0.116	+1.181	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Microtubule organizing center organization →	+0.082	+1.008	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,521 associations by consensus.

Protein localization to nuclear inner membrane by ZFR expression — KIDNEY

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