ZFPL1

Across TCGA pan-cancer cohorts, ZFPL1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ZFPL1 data layer compared with 22 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher ZFPL1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ZFPL1 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

CCRCC, PDAC, and LUAD are the cancer types where ZFPL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	II,III,IV	0.339	1.000	.003	36	view →
PDAC	DFS	Tertile	III,IV	0.900	0.248	.001	12	view →
LUAD	DFS	Median	All	0.533	0.717	.031	4	view →
UCEC	DFS	Quartile	All	0.902	1.000	.036	2	view →
LSCC	OS	Median	All	0.747	0.884	.044	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ZFPL1–CCRCC (OS)

Open the CCRCC breakdown →