ZFPL1

Across TCGA patient cohorts, ZFPL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,133 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible ZFPL1-associated GO terms across cancer lineages are Positive regulation of attachment of spindle microtubules to kinetochore, Regulation of centriole replication, and Spindle elongation. Each is linked with ZFPL1 in more than 23 cancer types. Because this analysis shows association rather than direction, both ZFPL1-to-partner and partner-to-ZFPL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of attachment of spindle microtubules to kinetochore grouped by ZFPL1-low versus ZFPL1-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFPL1→partner) and Y-score (partner→ZFPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Positive regulation of attachment of spindle microtubules to kinetochore →	+0.138	+0.887	<.001	<.001	3	24
DLBC	Regulation of centriole replication →	+0.076	+0.644	<.001	<.001	3	23
ESCA	Spindle elongation →	+0.099	+0.345	<.001	<.001	3	23
DLBC	Positive regulation of chromosome condensation →	+0.133	+0.720	<.001	<.001	3	23
DLBC	Meiotic chromosome condensation →	+0.139	+0.778	<.001	<.001	3	23
DLBC	DNA strand elongation involved in DNA replication →	+0.068	+0.559	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,133 associations by consensus.

Positive regulation of attachment of spindle microtubules to kinetochore by ZFPL1 expression — DLBC

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