Across TCGA patient cohorts, ZFP91 mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFP91-associated genes across cancer lineages are 4E-BP1, EGFR_pY1068, and Heregulin. Each is linked with ZFP91 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFP91-to-partner and partner-to-ZFP91 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP91→partner) and Y-score (partner→ZFP91) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.240	+1.459	.006	.012	3	2
UCEC	EGFR_pY1068 →	-0.194	-1.584	.017	.034	3	1
UCEC	Heregulin →	-0.096	-1.222	.016	.035	3	1
UCEC	JNK_pT183_Y185 →	-0.128	-1.415	.018	.043	3	1
UCEC	JNK2 →	+0.227	+2.000	<.001	<.001	3	1
UCEC	MEK1 →	+0.268	+2.321	.023	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

ZFP91 survival (RNA) · tumor vs normal (RNA) · all ZFP91 data types