Across TCGA pan-cancer cohorts, ZFP90 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ZFP90 data layer compared with 23 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher ZFP90 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ZFP90 expression acts as an unfavorable survival marker, although some lineages such as LSCC and CCRCC show a favorable association.

PDAC, HNSC, and LSCC are the cancer types where ZFP90 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Quartile	II,III,IV	0.365	0.770	.006	15	view →
HNSC	DFS	Quartile	III,IV	0.329	0.834	.014	12	view →
LSCC	DFS	Median	All	0.879	0.582	.009	10	view →
LUAD	DFS	Quartile	II,III,IV	0.609	1.000	.010	7	view →
CCRCC	DFS	Median	All	1.000	0.306	.014	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: ZFP90 tumor-vs-normal RNA expression · all ZFP90 data types