Across TCGA patient cohorts, ZFP90 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFP90-associated genes across cancer lineages are Notch1, EGFR_pY1068, and A-Raf_pS299. Each is linked with ZFP90 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFP90-to-partner and partner-to-ZFP90 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP90→partner) and Y-score (partner→ZFP90) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.204	+2.817	<.001	.001	3	2
UCEC	EGFR_pY1068 →	-0.214	-2.000	.015	.003	3	1
UCEC	A-Raf_pS299 →	-0.083	-2.000	.048	.030	3	1
UCEC	FoxM1 →	+0.249	+2.874	.006	<.001	3	1
UCEC	Gab2 →	+0.258	+1.362	.040	.037	3	1
UCEC	INPP4B →	-0.293	-2.700	.010	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Exploration

ZFP90 survival (RNA) · tumor vs normal (RNA) · all ZFP90 data types