ZFP82

Across TCGA patient cohorts, ZFP82 mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFP82-associated genes across cancer lineages are eIF4E, INPP4B, and Akt_pT308. Each is linked with ZFP82 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFP82-to-partner and partner-to-ZFP82 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by ZFP82-low versus ZFP82-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP82→partner) and Y-score (partner→ZFP82) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.169	+2.920	.006	<.001	3	2
UCEC	INPP4B →	-0.275	-2.247	.003	.001	3	2
UCEC	Akt_pT308 →	+0.505	+2.502	.006	.001	3	2
UCEC	Annexin-1 →	+0.434	+1.432	.005	.005	3	2
UCEC	Shc_pY317 →	-0.098	-1.058	.027	.037	3	2
UCEC	14-3-3_beta →	-0.078	-1.973	.008	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

eIF4E by ZFP82 expression — UCEC

Explore this box plot interactively →