ZFP64

Across TCGA patient cohorts, ZFP64 mutation is significantly associated with the total protein of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFP64-associated genes across cancer lineages are ASNS, Caspase-7-cleavedD198, and 4E-BP1. Each is linked with ZFP64 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZFP64-to-partner and partner-to-ZFP64 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by ZFP64-low versus ZFP64-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP64→partner) and Y-score (partner→ZFP64) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ASNS →	+0.544	+2.178	.003	.035	3	5
COAD	Caspase-7-cleavedD198 →	+1.599	+3.330	<.001	.005	3	3
UCEC	4E-BP1 →	+0.278	+3.169	<.001	<.001	3	3
COAD	Cyclin-E1 →	+0.296	+2.178	.012	.035	3	3
STAD	PDCD4 →	-0.420	-3.000	.035	.034	3	2
STAD	ATM →	-0.349	-2.321	.043	.034	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

ASNS by ZFP64 expression — COAD

Explore this box plot interactively →