ZFP64

Across TCGA cell cohorts, ZFP64 mutation is significantly associated with the RNA expression of many other genes, with 623 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZFP64-associated genes across cancer lineages are FBXW10, FCER1A, and LACTBL1. Each is linked with ZFP64 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFP64-to-partner and partner-to-ZFP64 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FBXW10 grouped by ZFP64-low versus ZFP64-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP64→partner) and Y-score (partner→ZFP64) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	FBXW10 →	+0.064	+3.938	<.001	.002	3	2
LUNG_SCLC	FCER1A →	+0.101	+3.628	<.001	.009	3	2
LUNG_NSCLC_LUAD	LACTBL1 →	+0.004	+3.604	<.001	.004	3	2
LARGE_INTESTINE	KLRG1 →	+0.499	+2.584	.004	.002	3	2
LARGE_INTESTINE	RPUSD3 →	+0.355	+3.321	.005	.003	3	2
LARGE_INTESTINE	NOP10 →	+0.471	+3.169	.005	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 623 associations by consensus.

FBXW10 by ZFP64 expression — BLOOD_Leukemia

Explore this box plot interactively →