Across TCGA patient cohorts, ZFP62 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFP62-associated genes across cancer lineages are Rad50, 14-3-3_beta, and EGFR_pY1068. Each is linked with ZFP62 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFP62-to-partner and partner-to-ZFP62 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP62→partner) and Y-score (partner→ZFP62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rad50 →	-0.228	-1.584	.009	.019	3	2
UCEC	14-3-3_beta →	-0.102	-3.432	.004	.005	3	1
UCEC	EGFR_pY1068 →	-0.238	-1.584	.008	.019	3	1
UCEC	ACC1 →	+0.329	+2.128	.011	.009	3	1
UCEC	JNK2 →	+0.255	+1.817	<.001	.015	3	1
UCEC	MEK1 →	+0.357	+2.584	.006	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

ZFP62 survival (RNA) · tumor vs normal (RNA) · all ZFP62 data types