Across TCGA cell cohorts, ZFP57 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZFP57-associated genes across cancer lineages are INSL5, ADAMDEC1, and SEMG2. Each is linked with ZFP57 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFP57-to-partner and partner-to-ZFP57 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP57→partner) and Y-score (partner→ZFP57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	INSL5 →	+0.242	+3.626	<.001	.006	3	2
SKIN	ADAMDEC1 →	+0.028	+4.095	.002	.009	3	1
LARGE_INTESTINE	SEMG2 →	+0.417	+2.878	.003	.009	3	1
LARGE_INTESTINE	TBC1D21 →	+0.008	+3.700	<.001	.009	3	1
LARGE_INTESTINE	CEACAM3 →	+0.734	+3.491	<.001	.008	3	1
LARGE_INTESTINE	UTF1 →	+0.015	+3.217	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

ZFP57 survival (RNA) · tumor vs normal (RNA) · all ZFP57 data types