ZFP37

Across TCGA cell cohorts, ZFP37 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,088 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ZFP37-associated GO terms across cancer lineages are Protein localization to ciliary membrane, Positive regulation of termination of RNA polymerase II transcription, and Positive regulation of termination of DNA-templated transcription. Each is linked with ZFP37 in more than 11 cancer types. Because this analysis shows association rather than direction, both ZFP37-to-partner and partner-to-ZFP37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to ciliary membrane grouped by ZFP37-low versus ZFP37-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP37→partner) and Y-score (partner→ZFP37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protein localization to ciliary membrane →	+0.105	+1.116	.003	.001	3	11
OESOPHAGUS	Positive regulation of termination of RNA polymerase II transcription →	+0.149	+0.905	.006	.001	2	12
OESOPHAGUS	Positive regulation of termination of DNA-templated transcription →	+0.149	+0.905	.006	.001	2	12
OVARY	Nucleotide-excision repair →	+0.055	+0.595	<.001	<.001	3	10
SKIN	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.068	+0.672	<.001	<.001	3	10
SKIN	mRNA splicing, via spliceosome →	+0.068	+0.672	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,088 associations by consensus.

Protein localization to ciliary membrane by ZFP37 expression — STOMACH

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