ZFP36L2

Across TCGA patient cohorts, ZFP36L2 mutation is significantly associated with the RNA expression of many other genes, with 327 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible ZFP36L2-associated genes across cancer lineages are VDAC2P1, DAZ3, and TSPY8. Each is linked with ZFP36L2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZFP36L2-to-partner and partner-to-ZFP36L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VDAC2P1 grouped by ZFP36L2-low versus ZFP36L2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP36L2→partner) and Y-score (partner→ZFP36L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	VDAC2P1 →	+0.132	+4.893	.001	.005	3	3
SCLC	DAZ3 →	+0.034	+5.189	<.001	.006	3	2
SCLC	TSPY8 →	+2.882	+5.189	<.001	.006	3	2
SCLC	TSPY4 →	+2.503	+5.624	<.001	.003	3	2
BRCA	FKBP4P8 →	+0.016	+4.215	<.001	.009	3	2
BRCA	RNU6-182P →	+0.547	+3.312	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 327 associations by consensus.

VDAC2P1 by ZFP36L2 expression — COAD

Explore this box plot interactively →