ZFP36L2

Across TCGA patient cohorts, ZFP36L2 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible ZFP36L2-associated genes across cancer lineages are Astrocytes, Tregs, and Chondrocytes. Each is linked with ZFP36L2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZFP36L2-to-partner and partner-to-ZFP36L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Astrocytes grouped by ZFP36L2-low versus ZFP36L2-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP36L2→partner) and Y-score (partner→ZFP36L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	Astrocytes →	+0.164	+5.479	<.001	.043	3	3
COAD	Tregs →	+0.024	+4.824	<.001	.045	3	2
UCEC	Chondrocytes →	+0.008	+2.286	.019	.042	3	2
UCEC	CD4+ memory T-cells →	+0.022	+2.617	.029	.008	3	2
BLCA	Adipocytes →	+0.025	+2.384	.045	.015	3	1
BLCA	NKT →	-0.100	-3.133	.027	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Astrocytes by ZFP36L2 expression — LIHC

Explore this box plot interactively →