ZFP36L2

Across TCGA cell cohorts, ZFP36L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,262 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ZFP36L2-associated GO terms across cancer lineages are Somatic stem cell division, 3'-UTR-mediated mRNA destabilization, and Positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. Each is linked with ZFP36L2 in more than 17 cancer types. Because this analysis shows association rather than direction, both ZFP36L2-to-partner and partner-to-ZFP36L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Somatic stem cell division grouped by ZFP36L2-low versus ZFP36L2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP36L2→partner) and Y-score (partner→ZFP36L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Somatic stem cell division →	+1.115	+1.994	<.001	<.001	3	18
URINARY_TRACT	3'-UTR-mediated mRNA destabilization →	+0.177	+1.501	<.001	<.001	3	15
STOMACH	Positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.170	+1.433	<.001	<.001	3	14
LIVER	ERK1 and ERK2 cascade →	+0.186	+1.178	.001	.002	3	14
URINARY_TRACT	Negative regulation of stem cell differentiation →	+0.150	+1.361	<.001	<.001	3	14
LUNG_SCLC	Cellular response to granulocyte macrophage colony-stimulating factor stimulus →	+1.213	+0.686	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,262 associations by consensus.

Somatic stem cell division by ZFP36L2 expression — BONE

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