Across TCGA patient cohorts, ZFP36L1 mutation is significantly associated with the total protein of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFP36L1-associated genes across cancer lineages are JNK_pT183_Y185, Caspase-7-cleavedD198, and Ku80. Each is linked with ZFP36L1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZFP36L1-to-partner and partner-to-ZFP36L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP36L1→partner) and Y-score (partner→ZFP36L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK_pT183_Y185 →	-0.169	-2.571	.008	.001	3	3
UCEC	Caspase-7-cleavedD198 →	+0.789	+2.242	<.001	.005	3	3
UCEC	Ku80 →	+0.209	+1.335	.021	.046	3	2
UCEC	PDCD4 →	-0.711	-2.087	<.001	.005	3	2
UCEC	4E-BP1_pT70 →	+0.108	+1.678	.014	.023	3	2
UCEC	4E-BP1 →	+0.522	+3.807	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

Exploration

ZFP36L1 survival (RNA) · tumor vs normal (RNA) · all ZFP36L1 data types