ZFP30

Across TCGA patient cohorts, ZFP30 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFP30-associated genes across cancer lineages are FoxM1, INPP4B, and PCNA. Each is linked with ZFP30 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFP30-to-partner and partner-to-ZFP30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by ZFP30-low versus ZFP30-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP30→partner) and Y-score (partner→ZFP30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.197	+1.222	.019	.035	3	2
UCEC	INPP4B →	-0.258	-2.415	.014	.002	3	2
UCEC	PCNA →	+0.224	+1.716	.001	.003	3	2
UCEC	PRAS40_pT246 →	+0.155	+2.115	.005	.016	3	2
UCEC	ASNS →	+0.410	+1.502	<.001	.027	3	2
UCEC	4E-BP1 →	+0.369	+2.277	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

FoxM1 by ZFP30 expression — UCEC

Explore this box plot interactively →