ZFP3

Across TCGA pan-cancer cohorts, ZFP3 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ZFP3 data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ZFP3 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ZFP3 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

LUAD, LSCC, and CCRCC are the cancer types where ZFP3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.818	0.451	.004	7	view →
LSCC	DFS	Quartile	All	0.942	0.572	.015	5	view →
CCRCC	DFS	Tertile	II,III,IV	0.797	0.279	.020	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ZFP3–LUAD (DFS)

Open the LUAD breakdown →