Across TCGA patient cohorts, ZFP28 mutation is significantly associated with the RNA expression of many other genes, with 1,844 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFP28-associated genes across cancer lineages are CHAF1B, FEN1, and SHCBP1. Each is linked with ZFP28 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZFP28-to-partner and partner-to-ZFP28 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP28→partner) and Y-score (partner→ZFP28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CHAF1B →	+0.484	+2.502	.001	.001	3	3
UCEC	FEN1 →	+0.588	+1.925	<.001	<.001	3	3
UCEC	SHCBP1 →	+0.485	+1.665	.002	.002	3	3
UCEC	ZBTB8OS →	+0.334	+1.925	<.001	<.001	3	3
UCEC	TIPIN →	+0.386	+2.191	.001	<.001	3	3
UCEC	CDC45 →	+0.587	+2.823	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,844 associations by consensus.

Exploration

ZFP28 survival (RNA) · tumor vs normal (RNA) · all ZFP28 data types